What is Somatuline® Depot (lanreotide) Injection?
Somatuline Depot is a prescription medicine used for:
Long-term treatment of adults with acromegaly when surgery or
radiotherapy has not worked well enough or the patient is not able
to have surgery or radiotherapy.
Treatment of adults with a type of cancer known as neuroendocrine
tumors, from the gastrointestinal tract or the pancreas (GEP-NETs)
that has spread or cannot be removed by surgery.
It is not known if Somatuline Depot is safe and effective in children.
You will receive a Somatuline Depot injection in your doctor’s office.
Somatuline Depot is injected deep under the skin of the upper outer area of
your buttock. Your injection site should change (alternate) between your
right and left buttock from one injection to the next.
IMPORTANT SAFETY INFORMATION
Who should not take Somatuline Depot?
Do not take Somatuline Depot if you are allergic to lanreotide.
Somatuline Depot may cause serious side effects including:
Changes in your blood sugar (high blood sugar or low blood sugar)
Slow heart rate
High blood pressure
The most common side effects of Somatuline Depot in:
People with acromegaly include diarrhea, gallstones, stomach area
(abdominal) pain, nausea, and pain, itching, or a lump at the injection
People with GEP-NETs include stomach area (abdominal) pain, muscle and
joint aches, vomiting, headache, and pain, itching, or a lump at the
These are not all the possible side effects of Somatuline Depot. Tell your
doctor if you have any side effect that bothers you or that does not go
Before you receive Somatuline Depot, talk to your doctor about:
All of your medical conditions, including
Gallbladder, heart, thyroid, kidney, or liver problems
Pregnancy or plans to become pregnant
It is not known if Somatuline Depot could harm your unborn baby
Breast-feeding or plans to breast-feed
It is not known if Somatuline Depot passes into breast milk
Any medicines (prescription and nonprescription) you are taking, including
Insulin or other diabetes medicines
A cyclosporine (such as Gengraf®, Neoral®, or Sandimmune®)
A medicine called bromocriptine (such as Parlodel® or Cycloset®)
Medicines that lower your heart rate (such as beta blockers)
You may report suspected adverse reactions to FDA at 1-800-FDA-1088 or
to Ipsen Biopharmaceuticals, Inc.